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The Red Sox are getting no favors to kick their title defense off this year. Baltimore gave them fits last year. They were the only AL East side to have a winning record against Boston, going 11-8. The Orioles have some solid pitching and a lineup that can mash the ball. To beat the Orioles you have to limit their power and not waste scoring chances. This isn't like playing Houston; leaving men on base against the Orioles is hard to overcome.
This is especially true considering whom the Sox face this afternoon. Chris Tillman came into his own last year, going 16-7 with a 3.71 ERA, a 4.4 WAR and his first All-Star appearance. He also flat-out owned Boston in 2013. He pitched six games against the Sox last year and went 3-1 with a 2.65 ERA, a 1.179 WHIP and a 3.08 K/BB ratio.
Yeah, this game isn't going to be easy.
The Sox are putting Jon Lester on the mound. The default "ace"* of the rotation, he saw a return to form last year going 15-8 with a 3.75 ERA. But against Baltimore he, like the Sox, struggled. In four starts against the Orioles Lester was 1-2 with a 4.70 ERA and a 1.478 WHIP. As well as Lester pitches against Toronto, that is how much trouble he has with Baltimore.